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Arbeitsgruppe Kemkemer |
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Mechanisms of force-induced dynamic cell reorganizations
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We try to obtain a profound understanding of molecular and biophysical processes in force-induced cellular responses (see e.g. Biophysical Journal, 95, 3470-78, 2008). Of special interest is the temporal and spatial dynamics of the cellular acto-myosin system and focal adhesion upon application of external forces and at the migration through confined 3D-like environments.
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| FRET image of Rho GTPase activity |
Deformation of pancreas tumor cells at the migration though small channels
Video: Klicken Sie auf das Bild oder den Link. |
Video: Deformation of pancreas tumor cells at the migration though small channels
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